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Evaluation of Regenerative Potential of Locally Delivered Vitamin C along with Microneedling in the Treatment of Deficient Interdental Papilla: A Clinical Study

J Contemp Dent Pract. 2022 May 1;23(5):503-507.


AIM: To evaluate the efficacy of intrapapillary injections of vitamin C along with microneedling (MN) in enhancing deficient interdental papilla (IDP) in esthetic zones clinically.

MATERIALS AND METHODS: Fifteen patients diagnosed with black triangles according to Norland classification system for loss of papillary height were selected. After oral prophylaxis and baseline measurements of insufficient interdental papilla, the vitamin C injection was loaded in disposable syringe 30G × 1/2″ needle. The needle was inserted at 45° angle, 2-3-mm apical to the involved papilla and all surrounding areas. Each involved papilla was injected with an amount till blanching was visible. After that, MN was done in the required area. This method was repeated for 5 times at 7 days intervals consecutively. The final clinical photographs and measurements were recorded after 7 days of last dose administered.

RESULTS: There was a statistically significant difference in the mean IDP height observed over the time period (p = 0.002).

CONCLUSION: An overall healthy appearance of gingiva with a remarkable increase in papilla growth was observed.

CLINICAL SIGNIFICANCE: Vitamin C injection along with MN can be considered as an alternative to invasive surgical procedures in reconstruction or regeneration of the missing IDP.


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