J Oral Pathol Med. 2022 Aug 23. doi: 10.1111/jop.13348. Online ahead of print.
ABSTRACT
BACKGROUND: The aim of this study is to analyze if the results of the Oral Health Impact Profile-14 questionnaire (OHIP-14) in patients with primary Sjögren’s syndrome (pSS) are correlated with salivary flow and level of xerostomia.
METHODS: This observational cross-sectional study was conducted in sixty-one patients (60 women, one man, mean age 57.64 (13.52)) diagnosed of pSS according to the American-European Criteria (2002). After recording demographic, medical and dental data (decayed-missing-filled teeth index (DMFT)), unstimulated (UWS) and stimulated (SWS) salivary flows were collected. Subsequently, UWS flow was categorized into two groups (<0.1 mL/min and ≥0.1mL/min) and SWS into three groups (<0.1 mL/min, 0.1-0.7 mL/min and >0.7 mL/min). Patients also filled out a visual analog scale (VAS) for xerostomia and OHIP-14 for self-reported quality of life (QoL).
RESULTS: Data showed positive and significant correlation between OHIP-14 and xerostomia, based on VAS results (r=0.52; p=0.001). Furthermore, there was a negative correlation between UWS and OHIP-14 scores (r=-0.34; p=0.006) and VAS for xerostomia (r=-0.22; p=0.09). No significant correlation was found between SWS and OHIP-14 or VAS neither between DMFT and OHIP-14. When assessing the level of QoL by the UWS and SWS flow categories a significant association was found for UWS (p=0.001) but not for SWS (p=0.11). The OHIP-14 values were higher in the groups with lower salivary flow. The multiple linear regression to predict OHIP-14 only selected VAS for xerostomia as a statistically significant predictor.
CONCLUSIONS: Increased level of xerostomia and reduced UWS flow decrease oral health-related QoL in patients with pSS.
PMID:35998227 | DOI:10.1111/jop.13348
