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Nevin Manimala Statistics

Practical application of mathematical calculations and statistical methods for the routine haematology laboratory

Int J Lab Hematol. 2022 Sep;44 Suppl 1:11-20. doi: 10.1111/ijlh.13934.

ABSTRACT

BACKGROUND: Statistical analyses are embedded as critical functions in the routine haematology laboratory.

AIM: This educational article is aimed at providing an overview of these topics and practical application examples.

MATERIALS, METHODS, AND RESULTS: Topics covered include mathematical conversion between units, maintaining a quality control (QC) system, statistical methods for reagent validation, and determining uncertainty of measurement (UoM).

DISCUSSION: Additional considerations may be required when a regional laboratory program is in place, such as the harmonization of INR results and determination of therapeutic reference intervals for unfractionated heparin therapy.

CONCLUSION: The coauthors of this manuscript are fortunate to be part of regional network of hospital laboratories, the Eastern Ontario Regional Laboratory Association (EORLA).

PMID:36074706 | DOI:10.1111/ijlh.13934

By Nevin Manimala

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