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Comparative Study of Clinical Characteristics of COVID-19 Patients with or without Digestive Symptoms in Razi Hospital, Ahvaz, Khuzestan

Endocr Metab Immune Disord Drug Targets. 2022 Aug 23. doi: 10.2174/1871530322666220823155956. Online ahead of print.


AIMS: The pandemic of coronavirus disease 2019 (COVID-19), has emerged as a dire health problem, causing a massive crisis for global health.

BACKGROUND: Most commonly reported clinical manifestations are fever, fatigue and dry cough. Interestingly, a small percentage of patients experience GI symptoms with the most common being anorexia, diarrhea, nausea and vomiting. We aimed to investigate a comparable study of COVID-19 patients with or without gastrointestinal patients (GI).

METHODS: Collective data of clinical manifestations and laboratory reports of patients admitted in Razi Hospital, Ahvaz, Khuzestan, Iran, during two weeks were analyzed.

RESULTS: Our results showed that GI symptoms are not statistically significant criteria to be predictive or prognostic factors in the COVID-19 patients despite they are probably related to acute or non-acute phase of the disease. Moreover, non-specific GI symptoms seem to be as a result of cytokine storm occurred during the disease.

CONCLUSION: Therefore, our results did not support GI tract involvement as a common route of COVID-19 infection. Maybe future research will shed light on why and how the gastrointestinal system became infected by COVID-19.

PMID:36125828 | DOI:10.2174/1871530322666220823155956

By Nevin Manimala

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