World Neurosurg. 2022 Oct 26:S1878-8750(22)01487-5. doi: 10.1016/j.wneu.2022.10.070. Online ahead of print.
BACKGROUND: The relationship between Roussouly type and Modic changes (MCs) is unknown. Thus, the aim of our study was to investigate the influence of Roussouly type on the characteristics of MCs in patients with lumbar degenerative disc disease (LDD).
METHODS: This cross-sectional observational study included 270 patients with LDD from Huashan Hospital. All the subjects were divided into four groups according to the Roussouly classification. The prevalence, subtype and distribution characteristics of MCs from L1-L2U to L5-S1L were compared between four Roussouly types.
RESULT: A total of 270 patients were included in our study, 65 cases (24.1%) of Roussouly type Ⅰ, 115 cases (42.6%) of Roussouly type Ⅱ, 55 cases (20.4%) of Roussouly type Ⅲ, and 35 cases (13.0%) of Roussouly type Ⅳ. MCs were present in 45.9% (n=270) subjects, 12.7% (n=2700) endplates and 11.8% (n=1350) intervertebral discs. The prevalence rate of MCs by subtype and intervertebral disc among four Roussouly types was statically different (P＜0.05) and the prevalence rate of MCs by intervertebral disc in Roussouly type Ⅰ was statistically higher than other three Roussouly types. In Roussouly type Ⅰ and Ⅳ, the prevalence rate of MCs at L4-L5 level showed no significant differences compared with those at upper lumbar levels while in Roussouly type Ⅱ and Ⅲ, the prevalence rate of MCs at L4-L5 level was significantly higher than those at upper lumbar levels.
CONCLUSION: We concluded that Roussouly types can influence the prevalence, subtype and distribution characteristics of MCs in patients with LDD.