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Inhibitory Effect of Traditional Endodontic Irrigants versus LED activated Photosensitizer Curcumin Microbes of Saudi Arabian Infected Dental Pulp

Mymensingh Med J. 2023 Jan;32(1):236-239.


The success of an endodontic therapy is combinational, dependent on mechanical preparation of canal and chemically detriment of microbial load. Therefore the use of an efficient irrigant is necessary having potential for eradicating the population dependent endodontic microbes. The main aim of the study was to evaluate and compare the antimicrobial potential of commonly used endodontic irrigants and LED light activated curcumin against the endodontic microbial variants of Saudi Arabian population. The 170 infected pulp samples were collected in nutrient broth and streaked on four types of agar plates for each sample after 24 hours of incubation at 37°C. Later after incubation for one day, the microbes were identified under the microscope and the number of microbial colonies. Using well method anti-microbial efficacy of three experimental groups with traditional endodontic irrigants (5.25% NaOCl, 2.0% CHX and 17.0% EDTA), LED light activated photosensitizer and one negative control (NaCl) was evaluated. The photosensitizer and 17.0% EDTA displayed to have efficient anti-microbial potential against E. fecalis and Streptococcal species reducing the colony count and increased radius of 4.3mm (Curcumin)/ 4.1mm (17.0% EDTA) and 3.2mm (Curcumin)/ 3.0mm (17.0% EDTA) showing anti-bacterial effect on the agar plates trailed by 5.25% NaOCl but statistically no significant difference was observed. On contrary 5.25% NaOCl showed strong potential against Staphylococcus and C. albicans species. Overall it can be concluded from the results 5.25% of NaOCl have stronger anti-microbial potential than 17.0% EDTA, CHX and NaCl against endodontic species of Saudi Arabian population.


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