Nevin Manimala Statistics

Overview of frequent pattern mining

Genomics Inform. 2022 Dec;20(4):e39. doi: 10.5808/gi.22074. Epub 2022 Dec 30.


Various methods of frequent pattern mining have been applied to genetic problems, specifically, to the combined association of two genotypes (a genotype pattern, or diplotype) at different DNA variants with disease. These methods have the ability to come up with a selection of genotype patterns that are more common in affected than unaffected individuals, and the assessment of statistical significance for these selected patterns poses some unique problems, which are briefly outlined here.

PMID:36617647 | DOI:10.5808/gi.22074

By Nevin Manimala

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