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Community pharmacist intervention to optimize statin adherence in diabetes care: The GuIDE-S study

J Am Pharm Assoc (2003). 2023 Mar 16:S1544-3191(23)00068-7. doi: 10.1016/j.japh.2023.03.002. Online ahead of print.


BACKGROUND: Statin use in people with type 2 diabetes (T2D) reduces cardiovascular events, yet adherence remains suboptimal.

OBJECTIVE(S): This study evaluated the impact of a community pharmacist intervention on statin adherence in new users with T2D.

METHODS: As part of a quasi-experimental study, community pharmacy staff proactively identified adult patients with T2D who were not prescribed a statin. When appropriate, the pharmacist prescribed a statin via a collaborative practice agreement or facilitated acquisition of a prescription from another prescriber. Patients received individualized education and follow up and monitoring for one year. Adherence was defined as the proportion of days covered (PDC) by a statin over 12 months. Linear and logistic regression were used to compare the effect of the intervention on continuous and a binary adherence threshold, defined as PDC > 80%, respectively.

RESULTS: Overall, 185 patients started statin therapy and were matched to 370 control patients for analysis. Adjusted average PDC was 3.1% higher in the intervention group (95% CI: -0.037, 0.098). Patients in the intervention group were 21.2% more likely to have PDC > 80% (95% CI: 0.828, 1.774).

CONCLUSION: The intervention resulted in higher statin adherence compared to usual care; however, the differences were not statistically significant.

PMID:36933697 | DOI:10.1016/j.japh.2023.03.002

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