Stat Methods Med Res. 2023 Jun 20:9622802231181224. doi: 10.1177/09622802231181224. Online ahead of print.
ABSTRACT
Censored data frequently appeared in applications across a variety of different areas like epidemiology or medical research. Traditionally statistical inference on this data mechanism was based on some pre-assigned models that will suffer from the risk of model-misspecification. This article proposes a two-folded shrinkage procedure for simultaneous structure identification and variable selection of the semiparametric accelerated failure additive model with right-censored data, in which the nonparametric functions are addressed by spline approximation. Under some regularity conditions, the consistency of model structure identification is theoretically established in the sense that the proposed method can automatically separate the linear and zero components from the nonlinear ones with probability approaching to one. Detailed issues in computation and turning parameter selection are also discussed. Finally, we illustrate the proposed method by some simulation studies and two real data applications to the primary biliary cirrhosis data and skin cutaneous melanoma data.
PMID:37338958 | DOI:10.1177/09622802231181224
