J Cataract Refract Surg. 2023 Jul 24. doi: 10.1097/j.jcrs.0000000000001270. Online ahead of print.
ABSTRACT
PURPOSE: To demonstrate the safety and efficacy of allogenic corneal inlays designed to increase the depth of focus in treated eyes.
SETTINGS: Medipol University Hospital, Istanbul, Turkey.
DESIGN: Prospective case series.
METHODS: This study includes 50 eyes of 25 patients with a follow-up of 3 years. Emmetropic patients with presbyopia had implantation of allogenic corneal inlays (Allotex) in the nondominant eye. The uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and uncorrected near visual acuity (UNVA) were evaluated in all eyes. A subjective visual acuity test system (Multifocal Lens Analyzer 3.0 application, Q Vision Academy, Spain) was used to analyze the depth of focus by measuring the defocus curves.
RESULTS: No significant difference between the treated and fellow eyes in UDVA and CDVA was found, whereas UNVA was significantly better in the treated eyes (p=0.20, p=0.07, p<0.01, respectively). Comparing to the preoperative CDVA, there was a 1-line decrease in CDVA in 6 (%24) patients. The mean defocus curves reveal a depth of focus of 1.1D for the untreated eye at the logMAR=0.2 threshold. By contrast, the mean depth of focus of the treated eye and binocularly was 2.8D. The areas under the curve were significantly better in the near, intermediate, and total distances in the treated eyes, whereas it was better for the far distances in the untreated eyes. All values were significant (p=0.023 total, p<0.01 others).
CONCLUSIONS: Allogenic presbyopic inlay implantation may be safe and provided a clinically and statistically significant increase in the depth of focus leading to good far, intermediate, and near-visual acuity in emmetropic presbyopic patients.
PMID:37487178 | DOI:10.1097/j.jcrs.0000000000001270
