Nevin Manimala Statistics

Standardized Image-Based Polysomnography Database and Deep Learning Algorithm for Sleep Stage Classification

Sleep. 2023 Sep 13:zsad242. doi: 10.1093/sleep/zsad242. Online ahead of print.


STUDY OBJECTIVES: Polysomnography (PSG) scoring is labor intensive, subjective, and often ambiguous. Recently several deep learning (DL) models for automated sleep scoring have been developed, they are tied to a fixed amount of input channels and resolution. In this study, we constructed a standardized image-based PSG dataset in order to overcome the heterogeneity of raw signal data obtained from various PSG devices and various sleep laboratory environments.

METHODS: All individually exported European data format files containing raw signals were converted into images with an annotation file, which contained the demographics, diagnoses, and sleep statistics. An image-based DL model for automatic sleep staging was developed, compared with a signal-based model and validated in an external dataset.

RESULTS: We constructed 10,253 image-based PSG datasets using a standardized format. Among these, 7,745 diagnostic PSG data were used to develop our DL model. The DL model using the image dataset showed similar performance to the signal-based dataset for the same subject. The overall DL accuracy was greater than 80%, even with severe obstructive sleep apnea. Moreover, for the first time, we showed explainable DL in the field of sleep medicine as visualized key inference regions using Eigen-class activation maps. Furthermore, when a DL model for sleep scoring performs external validation, we achieved a relatively good performance.

CONCLUSION: Our main contribution demonstrates the availability of a standardized image-based dataset, and highlights that changing the data sampling rate or number of sensors may not require retraining, although performance decreases slightly as the number of sensors decreases.

PMID:37703391 | DOI:10.1093/sleep/zsad242

By Nevin Manimala

Portfolio Website for Nevin Manimala