Nevin Manimala Statistics

Repeatability and Agreement of Chord Mu Between Scheimpflug Tomography and Swept-source Optical Coherence Tomography

Korean J Ophthalmol. 2023 Oct 25. doi: 10.3341/kjo.2023.0092. Online ahead of print.


PURPOSE: To evaluate repeatability and agreemeny of chord mu between Scheimpflug tomography (Pentacam HR, Oculus Optikgeräte GmbH, Wetzlar, Germany) and swept-source optical coherence tomography-based optical biometer (IOLMaster 700, Carl Zeiss Meditec AG, Jena, Germany).

METHOD: In this retrospective study, 63 eyes of 33 patients were included. Chord mu, X, and Y Cartesian distances between the corneal vertex and the pupil center (Px and Py), and the pupil diameter were compared using two instruments. Repeatability was evaluated using intraclass correlation coefficient (ICC), coefficient of variation (CoV), and within-subject standard deviation (Sw). Inter-device agreement was evaluated using paired t-tests and Bland-Altman plots.

RESULTS: Although Sw values for all parameters were similar between the two devices, CoV values of chord mu and pupil diameter were lower, and ICC values of those parameters were higher, in the IOLMaster 700 than in the Pentacam HR. Chord mu and pupil diameter values were higher in IOLMaster 700 than Pentacam HR (p < 0.01). The width of the 95% limit of agreement was wide for all parameters.

CONCLUSION: IOLMaster 700 showed better repeatability than Pentacam HR in chord mu, Px, Py, and pupil diameter values. Because there were statistically significant differences and a low level of agreement in chord mu and pupil diameter values between the two devices, they cannot be used interchangeably.

PMID:37899279 | DOI:10.3341/kjo.2023.0092

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