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Clinical profile of corneal sensitivity in diabetic patients: A case-control study

J Fr Ophtalmol. 2024 May 23;47(7):104212. doi: 10.1016/j.jfo.2024.104212. Online ahead of print.


PURPOSE: To evaluate the corneal sensitivity of black diabetic patients and identify factors associated with changes in corneal sensitivity.

METHODOLOGY: We conducted a cross-sectional comparative case-control study at the National Obesity Center of the Yaounde Central Hospital and the Djoungolo District Hospital from March 1 to July 31, 2022. Corneal sensitivity was measured using the Cochet-Bonnet esthesiometer in all diabetic patients over 18 years of age, matched for age and sex to a clinically healthy control population. Data were analyzed using SPSS version 23.0 software. A P-value of less than 5% was considered significant.

RESULTS: A total of 111 diabetic and 111 non-diabetic patients participated in the study. The mean age was 53.46±12.74 years for diabetics and 52.85±11.77 years for non-diabetics (P=0.901). The mean duration of diabetes was 6.4±5.30 years. Corneal sensitivity in diabetics was lower (44.56±9.59mm) compared to non-diabetics (53.59±6.30mm) with a statistically significant difference (P=0.000). Factors associated with decrease in corneal sensitivity in diabetics were duration of diabetes and poor glycemic control.

CONCLUSION: Decrease in corneal sensitivity related to diabetes is a complication to be systematically screened for during the ophthalmologic follow-up of diabetic patients.

PMID:38788250 | DOI:10.1016/j.jfo.2024.104212

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