J Comp Eff Res. 2026 May 5:e260074. doi: 10.57264/cer-2026-0074. Online ahead of print.
ABSTRACT
In this update, we review a framework for identifying and mitigating information bias in electronic health records and administrative claims data, highlighting practical recommendations for study design, variable definition, and statistical analysis. We also discuss a perspective on emerging privacy-preserving technologies – synthetic data and federated networks – that enable secure cross-border data access while maintaining patient privacy.
PMID:42083917 | DOI:10.57264/cer-2026-0074