Categories
Nevin Manimala Statistics

Assessing the Effects of Microgravity on Eukaryotic Cells Using a Statistical Thermodynamic Approach

Methods Mol Biol. 2026;3000:47-60. doi: 10.1007/978-1-0716-5174-2_3.

ABSTRACT

This chapter has the aim to propose a theoretical framework for describing the qualitative changes in the deformation behavior of isolated human breast cancer cells under varying gravitational conditions. We describe interdisciplinary principles of statistical thermodynamics and nonlinear dynamics of eukaryotic cells. The framework aims to capture how microgravity-induced alterations in cytoskeletal organization lead to distinct mechanobiological phenotypes.

PMID:42151673 | DOI:10.1007/978-1-0716-5174-2_3

By Nevin Manimala

Portfolio Website for Nevin Manimala