Clin Oral Investig. 2026 Jun 4;30(6):275. doi: 10.1007/s00784-026-06959-9.
ABSTRACT
OBJECTIVES: This study aimed to evaluate the clinical effectiveness and safety of guided bone regeneration (GBR) using a three-dimensional preformed resorbable Polylactic-co-glycolic acid membrane (3D-PRPM) with simultaneous implant placement.
MATERIALS AND METHODS: Twenty patients (21 sites) with localized ridge defects were treated using implants placed concurrently with GBR using a 3D-PRPM. Cone-beam computed tomography scans were taken preoperatively, immediately postoperatively, and at 5 months. Horizontal bone augmentation (BA), hard tissue gain (HG), bone resorption (BR), and hard tissue gain rate (HGR) were assessed. Changes beyond the original bony envelope were evaluated. Statistical analyses included the Wilcoxon signed-rank and Friedman tests.
RESULTS: Mean BA was 2.99 ± 1.15 mm, and mean HG at 5 months was 2.64 ± 1.10 mm. Mean BR was 0.35 ± 0.23 mm, and mean HGR was 87.2% ± 8.2%. Envelope analysis confirmed a significant increase after augmentation with partial reduction during healing; however, ridge dimensions at 5 months remained significantly greater than baseline (P < 0.001). No membrane exposure, infection, or wound dehiscence occurred.
CONCLUSION: 3D-PRPM enabled predictable horizontal ridge augmentation with excellent volumetric stability and favorable short-term safety.
CLINICAL RELEVANCE: A 3D-PRPM may provide a stable, fixation-free resorbable barrier for horizontal ridge augmentation, potentially simplifying GBR procedures and reducing the need for secondary removal.
PMID:42240865 | DOI:10.1007/s00784-026-06959-9
