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Nevin Manimala Statistics

Assessment of facial emotion recognition accuracy and reaction time in patients with social anxiety disorder diagnosed with performance-only specifier

J Clin Exp Neuropsychol. 2026 Jul 4:1-15. doi: 10.1080/13803395.2026.2697724. Online ahead of print.

ABSTRACT

AIM: To compare the facial emotion recognition (FER) accuracy and reaction time (RT) of patients with performance-type social anxiety disorder (pSAD) and generalized-type social anxiety disorder (gSAD) with healthy controls (HCs).

METHOD: A total of 56 patients who were diagnosed as having SAD (31 gSAD and, 25 pSAD) according to the diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) were included in the study. Forty individuals with no psychiatric disorders were included as the HCs. FER skills were assessed using a task that included Ekman’s basic emotions and a neutral face. Additionally, the Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), and the Liebowitz Social Anxiety Scale (LSAS) were administered to all participants.

RESULTS: FER performances of patients with pSAD were similar to the HC group. The accuracy rates for emotions other than sadness in patients with gSAD were similar to those in the HC group. The RT to all facial expressions in patients with gSAD was statistically significantly shorter than in the HCs (p < 0.005). The RT given to facial emotions other than sadness was shorter in the pSAD patient group compared with the HC group. A negative correlation was found between STAI-state anxiety and neutral face recognition. (r = -0.308, p < 0.05). However, except for neutral face recognition, no significant correlation was observed between the BDI, STAI-state, STAI-trait, LSAS-fear, LSAS-avoidance, and FERT subscales.

CONCLUSION: The current study casts doubt on some of the effects reported in the literature on SAD’s FER ability. In this study, no significant difference was found in FER ability among SAD subtypes; this may suggest that a common mechanism exists in both subtypes.

PMID:42400335 | DOI:10.1080/13803395.2026.2697724

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Nevin Manimala Statistics

Savor-Aging: The Art of Savoring Positive Emotions in Older Adulthood-A Randomized Controlled Trial

Appl Psychol Health Well Being. 2026 Aug;18(4):e70184. doi: 10.1111/aphw.70184.

ABSTRACT

Savoring has been identified as a promising strategy to foster emotional and psychological well-being and to reduce depression in elders. However, research on online savoring interventions for this population remains limited. This registered RCT aimed to examine the effectiveness of a 3-week online intervention (six activities), Savor-Aging, in promoting subjective and psychological well-being and reducing depressive symptoms. Seventy-six healthy older adults (M = 69.9, SD = 4.8) were randomly assigned to a savoring group or a positive emotion (PE) group. Life satisfaction, positive and negative affect, flourishing, and depression were assessed at baseline (T0), post-intervention (T1), and 1-month follow-up (T2) to test psychological changes. Longitudinal quantitative data were analyzed using linear mixed-effects models, whereas qualitative feedback was thematically analyzed. Significant overall time effects emerged for negative affect and depressive symptoms. Although most time × group interactions were not significant, the savoring condition showed more consistent improvements over time, including reductions in negative affect and depressive symptoms that were maintained at follow-up. Significant time effects emerged for flourishing only in the savoring group immediately after the intervention. Participants described the savoring intervention as pleasant, engaging, and meaningful. Overall, Savor-Aging appears to be a feasible and effective self-help intervention to support emotional well-being and reduce depression in older adults, offering an accessible approach to positive aging.

PMID:42400304 | DOI:10.1111/aphw.70184

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Nevin Manimala Statistics

Value of Genetically Rare Cord Blood Units Beyond Conventional Quality Metrics

HLA. 2026 Jul;108(1):e70817. doi: 10.1111/tan.70817.

ABSTRACT

Allogeneic haematopoietic stem cell transplantation (HSCT) is a cornerstone therapy for haematological and genetic disorders. Owing to the limited availability of HLA-identical related donors, umbilical cord blood (UCB) has become a valuable alternative source of haematopoietic progenitors. However, many UCB units are excluded from banking based on quality criteria, despite potentially harbouring rare and underrepresented HLA profiles, particularly within certain demographic groups. This study evaluated the strategic value of immunogenetically rare but low-quality UCB units in expanding donor options for patients with uncommon HLA profiles. HLA-A, -B, and -DRB1 typing was performed on 577 UCB units, and allelic, haplotypic, and genetic diversity analyses were conducted using the HLA-net GENE[RATE] tool. Units were categorised using the Search Prognosis Application as good (6/6), fair (5/6), or poor (< 5/6 matches). Genotype frequency was used as a proxy for immunogenetic rarity and evaluated as an operational criterion for defining retention thresholds. ROC analyses were interpreted as concordance analyses between genotype frequency and Search Prognosis classification rather than as independent predictive validation. Statistical significance was assessed by chi-square and residual analyses. The cohort displayed remarkable allelic diversity, particularly at the HLA-B locus, strong linkage disequilibrium among loci, and a large proportion of unique genotypes. Matching-prognosis classification identified 66.72% of units as good, 31.54% as fair, and 1.73% as poor. Caucasian genotypes were overrepresented in the good category, whereas Asian-Pacific-Islander and African-American haplotypes were enriched in poorer matching-prognosis categories. ROC analysis showed strong concordance between genotype frequency and Search Prognosis classification (AUC 0.80-0.99) and population-specific genotype frequency thresholds. Our findings suggest that immunogenetic rarity provides complementary value to conventional quality metrics. While low-cell-dose units may have limited direct clinical utility, those with rare HLA genotypes may retain strategic importance, particularly for patients with uncommon immunogenetic profiles. Integrative approaches combining biological and immunogenetic parameters may improve cord blood banking strategies.

PMID:42400301 | DOI:10.1111/tan.70817

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Nevin Manimala Statistics

From cognition to action: Exploring factors associated with dietary management behaviors in patients with inflammatory bowel disease via path model construction

J Health Psychol. 2026 Jul 4:13591053261462435. doi: 10.1177/13591053261462435. Online ahead of print.

ABSTRACT

This study examined the current status of dietary management behavior in patients with inflammatory bowel disease (IBD) and explored factors associated with these behaviors using Partial Least Squares Structural Equation Modeling, guided by the Temporal Self-regulation Theory. Validated scales were employed to assess dietary beliefs, consideration of future consequences, intention, habit, self-regulation capacity and dietary management behaviors in patients with IBD. The results indicated that intention was associated with dietary management behaviors and showed indirect associations between dietary beliefs and dietary management behaviors, as well as between consideration of future consequences and dietary management behaviors. The moderating effects of habit and self-regulation capacity on the association between intention and dietary management behaviors were not statistically significant. These findings suggest that dietary beliefs, consideration of future consequences, intention, habit, and self-regulation capacity are associated with dietary management behaviors among patients with IBD. These results provide implications for the development of supportive strategies for dietary self-management in patients with IBD.

PMID:42400280 | DOI:10.1177/13591053261462435

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Nevin Manimala Statistics

Predictive Factors and Survival Outcomes of Nasogastric Tube Removal in Community-Dwelling Residents: A Retrospective Cohort Study

J Appl Gerontol. 2026 Aug;45(8):1615-1624. doi: 10.1177/07334648251383625. Epub 2025 Oct 14.

ABSTRACT

ObjectivesTo develop a predictive model for nasogastric tube (NGT) removal and examine survival-related factors among community-dwelling residents.DesignRetrospective cohort study (2016-2020) using medical records.Setting and ParticipantsA total of 255 home care residents with NGTs from a regional hospital in Taiwan.MethodsThis retrospective study was conducted to identify predictors across 30 variables from clinical records and nursing assessments. Logistic regression and Cox proportional hazards models assessed predictors of successful NGT removal, with model performance evaluated using ROC curve.ResultsKey predictors of successful NGT removal (18.0%, n = 46) and 12-month survival were activities of daily living, instrumental activities of daily living, and upper limb strength. Survival was higher in the removal group, and the model showed good accuracy (AUC = 0.811).ConclusionThis model provides a clinically applicable tool that incorporates functional and medical indicators to assess NGT removal readiness, demonstrating strong predictive validity.

PMID:42400250 | DOI:10.1177/07334648251383625

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Nevin Manimala Statistics

Family-Centred Breastfeeding Interventions to Improve Exclusive Breastfeeding: A Systematic Review and Meta-Analysis

Nurs Open. 2026 Jul;13(7):e70669. doi: 10.1002/nop2.70669.

ABSTRACT

AIMS: To explore the effects of different family breastfeeding interventions on improving exclusive breastfeeding rates from 0 to 6 months postpartum and to identify the key characteristics of effective interventions.

METHODS: This systematic review and meta-analysis follows the Cochrane Handbook for Systematic Reviews of Interventions. The risk of bias in the included studies was assessed using the Cochrane Risk of Bias 2 (RoB 2) tool.

RESULTS: Nineteen studies were included in this systematic review. Family-based interventions significantly improved exclusive breastfeeding rates at 6 months postpartum compared with routine care (OR = 2.93, 95% CI [1.90, 4.50], p < 0.001). Interventions underpinned by theoretical frameworks enhanced exclusive breastfeeding within 2 months postpartum compared with non-theoretical ones (OR = 5.50, 95% CI [2.30, 13.19], p < 0.001). Multi-component interventions were more effective than single-method approaches (OR = 2.70, 95% CI [2.04, 3.57], p < 0.001). Programmes spanning both prenatal and postnatal periods achieved higher exclusive breastfeeding rates at 4-6 months than those implemented in a single phase (OR = 4.84, 95% CI [2.50, 9.40], p < 0.001).

CONCLUSIONS: Family-based breastfeeding interventions could improve exclusive breastfeeding rates within the first 6 months postpartum. Future breastfeeding interventions should include key family members, consider the guidance of theoretical frameworks on the intervention design, cover both the prenatal and postnatal periods, and use multiple methods to meet the needs of breastfeeding families.

IMPLICATIONS FOR NURSING PRACTICE: Nurses, midwives, lactation nurses, and public health nurses should actively involve fathers, grandparents, and other key family members in breastfeeding education and support. Family-centred breastfeeding interventions may help improve exclusive breastfeeding outcomes and strengthen family support for breastfeeding.

REGISTRATION: Not registered.

PMID:42400223 | DOI:10.1002/nop2.70669

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Nevin Manimala Statistics

Inflammatory Indices and Pediatric Emergence Delirium: Predictive Signal or Statistical Artifact?

Paediatr Anaesth. 2026 Jul 3. doi: 10.1002/pan.70259. Online ahead of print.

NO ABSTRACT

PMID:42400216 | DOI:10.1002/pan.70259

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Nevin Manimala Statistics

What Is Going on? The Purpose, Organisation and Supervision of Australian First-Year Nursing Students on Clinical Placements in Nursing Homes

Nurs Open. 2026 Jul;13(7):e70667. doi: 10.1002/nop2.70667.

ABSTRACT

AIM: Exploration of factors associated with clinical placements in nursing homes for first-year nursing students which may impact their career choices.

DESIGN: This paper reports on Stage I of a larger study which comprised a 2-stage sequential mixed-methods design.

METHODS: Stage I was a national survey conducted as a telephone interview with nurse academics involved in arranging clinical placements for first-year student nurses; and Stage II which included: interviews with student nurses before and after their first clinical placement in a nursing home, and interviews with clinical supervisors. The Stage I national survey was conducted as a telephone interview and was audio recorded. Transcripts of the interviews were analysed using descriptive statistics, content analysis, and reflexive thematic analysis.

RESULTS: All Australian nursing schools that offered a Bachelor of Nursing in 2023 were invited to participate. Twenty-nine (81%) participated. The first clinical placement for most (79%) Australian student nurses is in a nursing home. Four themes were identified from the data analysis: (1) clinical placements are increasingly organised by centralised teams (48%); (2) the supervision model and the clinical supervisor are determined by placement agreements where students can be supervised by someone ill equipped for the role; (3) the purpose of this first-year clinical placement is difficult to articulate, other than to practise fundamental skills; and (4) nursing homes can provide positive learning experiences for student nurses, if they are prepared for the setting and supervised appropriately.

CONCLUSION: While many of these findings have been documented for decades, clinical placements in nursing homes may provide student nurses with valuable experiences. Schools of nursing need to better prepare students for clinical placements in nursing homes (especially if it is their first clinical placement) and ensure they are appropriately supervised. If not, graduate nurses will not consider aged care nursing as a career option.

IMPLICATIONS FOR PRACTICE: These findings should encourage nursing schools to reconsider their curriculum design, especially the timing of clinical placements in nursing homes, and their employment of clinical supervisors. The Australian Nursing and Midwifery Accreditation Council (ANMAC) should mandate a care of older persons subject in all undergraduate nursing curricula to be undertaken before students undertake a clinical placement in a nursing home.

PUBLIC CONTRIBUTION: There was no public contribution to this research. All participants were nurse academics from participating Australian schools of nursing.

PMID:42400213 | DOI:10.1002/nop2.70667

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Nevin Manimala Statistics

Perspectives in Pediatric Ambulatory Anesthesia: Part 1-One Center’s 15 Year Evolution in Eligibility, Utilization, Efficiency, and Outcomes

Paediatr Anaesth. 2026 Jul 3. doi: 10.1002/pan.70254. Online ahead of print.

ABSTRACT

INTRODUCTION: Ambulatory surgery has become the dominant model of surgical care in the United States as surgical procedures increasingly shifted from inpatient to outpatient sites of practice. Similar growth in volumes has been observed in pediatric practice. Investigators have highlighted the challenges and opportunities in this current climate, including increasing medical and procedural complexity, difficulties matching pediatric-specific resources to meet the child’s perioperative needs and unique risk profile, and limited availability of pediatric ambulatory surgical and anesthesia guidelines of care. Further, they call out the complete lack of pediatric outcomes data to help inform the creation and modification of national care guidelines.

METHODS: To address these challenges, we chose to complete a comprehensive, single center retrospective review of our process, outcome, and balancing metrics contained in our EMR from our free-standing pediatric ambulatory surgery center (ASC) since its opening in July 2010 through December 2024. A commercial software system extracted de-identified, aggregated health data from the system’s EMR. The data are processed and presented in statistical process control charts. This methodology allows clinicians to distinguish between common cause and special cause variation.

RESULTS: Patient and procedural acuity increased as the system matured via lower age cutoffs and higher ASA physical status scores. This higher acuity was managed with a dynamic and evolving screening process, resulting in no change in unplanned emergency visit or hospital admissions. The COVID-19 pandemic had profound impacts on ASC operations and case mix, including a temporary closure.

DISCUSSION: This retrospective, observational assessment created a detailed picture of our ASC practice changes over time. A pediatric-specific ASC with appropriate patient selection processes, practice guidelines, and clinical expertise successfully mitigated the risk of complications. These results are not generalizable to non-academic, community ambulatory facilities due to the unique characteristics of our pediatric-specific academic center.

PMID:42400211 | DOI:10.1002/pan.70254

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Nevin Manimala Statistics

Perspectives in Pediatric Ambulatory Anesthesia: Part 2-One Center’s 15 Year Experience Improving Quality and Safety Outcomes

Paediatr Anaesth. 2026 Jul 3. doi: 10.1002/pan.70252. Online ahead of print.

ABSTRACT

INTRODUCTION: Pediatric ambulatory surgery has become the dominant model of surgical care in the United States, driven primarily by economic forces. There is variability in regional practice patterns, quality improvement cycles, and outcomes. Opportunity exists to overcome knowledge gaps and provide sustainable pathways of quality improvement. Our unique capability of describing the evolution of our pediatric ambulatory quality improvement practice allows us to contribute a single center’s perspective.

METHODS: We chose to complete a comprehensive retrospective review of our quality improvement process, outcome, and balancing metrics contained in our electronic health record (EHR) from our free-standing pediatric ambulatory surgery center (ASC) from July 2010 through December 2024. A commercial software system extracted de-identified, aggregated health data from the system’s EHR. The data are processed and presented in statistical process control charts. This methodology allows clinicians to distinguish between common cause and special cause variation.

RESULTS: Improvement themes (opioid-free anesthesia and stewardship, enhanced recovery, environmental efforts, positive deviance, and learning healthcare system) are described. Improvements in all six domains of quality (effectiveness, efficiency/timeliness, patient experience, equity, and safety) are illustrated with reliable sustainability. Our system achieved approximately a 13-fold increase in quality improvement (QI) project completion rate with self-serve, real-world data access; enabling the team to take on improvement tasks previously deemed too big, lengthy, or risky to complete.

DISCUSSION: We provide preliminary evidence that these methods may be generalizable. Requirements include engaged leadership, a standard framework for improvement with experienced leadership or accessible support, and easy access to real-world electronic medical record data (i.e., learning healthcare system [LHS]). Lastly, leaders must create a culture supportive of teamwork, change, and continuous improvement. Systems facilitate adoption and hinder resistance to standards, always with implementation and sustainability in mind. Meaningful, large-scale improvements in healthcare outcomes require collaboration across LHSs.

PMID:42400184 | DOI:10.1002/pan.70252