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DisCoVisc substituted for perfluorocarbon liquid stabilizing the detached retina during vitrectomy for rhegmatogenous retinal detachment

Retina. 2025 Jul 23. doi: 10.1097/IAE.0000000000004617. Online ahead of print.

ABSTRACT

PURPOSE: To investigate the effectiveness of using DisCoVisc as an alternative to perfluorocarbon liquid (PFCL) in stabilizing the detached retina during rhegmatogenous retinal detachment (RRD) surgery.

METHODS: Thirty eyes of 30 patients with RRD underwent the DisCoVisc technique for stabilizing the detached retina. Following intraoperative air-fluid exchange and the aspiration of subretinal fluid, DisCoVisc was applied to seal retinal breaks, thereby stabilizing the detached retina. Subsequent removal of the peripheral and basal vitreous was then performed. Intraoperative vitrectomy duration, retinal reattachment rate, postoperative best-corrected visual acuity (BCVA), intraocular pressure (IOP), and intraoperative and postoperative complications were analyzed.

RESULTS: Retinal reattachment was achieved in 28 eyes (28/30, 93.3%). The base of the vitreous was removed with a mean time of 10.17±2.94 min, and the total vitrectomy time was 22.93±4.97 min. At the last follow-up, the BCVA was 0.74±0.70 LogMAR, showing a significant improvement over the preoperative value of 1.44±1.25 LogMAR (Z=2.700, P=0.007). On the first postoperative day, the IOP was measured at 25.71±12.41 mmHg, exhibiting a statistically significant elevation compared to the preoperative IOP of 13.94±5.23 mmHg (P=0.000). There was no statistical difference in IOP at the last follow-up 14.01±2.68 mmHg compared to the preoperative IOP of 13.94±5.23 mmHg (P = 0.923). One patient developed macular hole after the operation, and there were no obvious complications during the operation.

CONCLUSIONS: DisCoVisc can effectively stabilize the detached retina during vitrectomy for RRD. Most significantly, it eliminated the risk of subfoveal PFCL residue-related complications.

PMID:40712142 | DOI:10.1097/IAE.0000000000004617

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Design and validation of a questionnaire to measure access to and quality of abortion services in Argentina

Salud Colect. 2025 Apr 22;21:e5348. doi: 10.18294/sc.2025.5348.

ABSTRACT

In Argentina, Law 27610, which legalized voluntary termination of pregnancy, was the result of years of activism and political alliances. To monitor its implementation, between 2022 and 2024 an instrument was developed to assess the accessibility and quality of abortion services, considering users’ experiences. We conducted a three-phase study that included expert panels, cognitive interviews, and a pilot test of the instrument with individuals who had undergone abortions. These efforts led to the creation of the questionnaire Measuring Accessibility and Quality in Abortion Services (MACA), which can be applied within the Argentine health system. This questionnaire can be used for monitoring purposes, to identify areas for improvement in health services, and to detect inequalities in access based on geographic and social characteristics.

PMID:40712120 | DOI:10.18294/sc.2025.5348

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Impact of preoperative double-J stent placement on stone recurrence following flexible ureteroscopic lithotripsy

J Int Med Res. 2025 Jul;53(7):3000605251359610. doi: 10.1177/03000605251359610. Epub 2025 Jul 25.

ABSTRACT

ObjectiveThis study investigated the effect of preoperative double-J stent placement on stone recurrence following flexible ureteroscopic lithotripsy and analyzed the risk factors for postoperative stone recurrence. The study aimed to provide a clinical reference for better management of the identified risk factors.MethodsThis retrospective study collected data from patients who underwent flexible ureteroscopic lithotripsy for urinary stones between April 2023 and May 2024. Patients were divided into two groups based on whether a double-J stent was placed preoperatively. Comparisons were made between the stent and nonstent groups. Univariate and multivariate logistic regression analyses were performed to identify the risk factors for postoperative stone recurrence.ResultsThe recurrence rate was 19.51% in the nonstent group and 1.47% in the stent group, with a statistically significant difference (P = 0.001). Stone removal strategy (P < 0.001), preoperative systolic blood pressure (P = 0.017), and intraoperative blood loss (P = 0.044) were identified as risk factors for postoperative recurrence, with stone removal strategy (P = 0.013) and preoperative systolic blood pressure (P = 0.017) being independent risk factors.ConclusionsPreoperative placement of a double-J stent is associated with a lower recurrence rate of stones following flexible ureteroscopic lithotripsy than no preoperative stenting. Stone removal strategy and preoperative systolic blood pressure are independent risk factors for stone recurrence following flexible ureteroscopic lithotripsy.

PMID:40712089 | DOI:10.1177/03000605251359610

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National Vital Statistics Reports

Natl Vital Stat Rep. 2025 Jun 17;(8):1. doi: 10.15620/cdc/174593.

ABSTRACT

OBJECTIVES: This report presents 2023 fetal mortality data by maternal race and Hispanic origin, age, tobacco use during pregnancy, and state of residence, as well as by plurality, sex, gestational age, birthweight, and selected causes of death. Trends in fetal mortality are also examined.

METHODS: Descriptive tabulations of data are presented and interpreted for all fetal deaths reported for the United States for 2023 with a stated or presumed period of gestation of 20 weeks or more. Cause-of-fetal-death data only are restricted to residents of the 38 states and District of Columbia where cause of death was based on the 2003 fetal death report revision for the full year and less than 50% of deaths were attributed to Fetal death of unspecified cause (P95).

RESULTS: A total of 20,005 fetal deaths at 20 weeks of gestation or more were reported in the United States in 2023. The 2023 U.S. fetal mortality rate was 5.53 fetal deaths at 20 weeks of gestation or more per 1,000 live births and fetal deaths, not significantly different from the rate of 5.48 in 2022. The fetal mortality rate in 2023 for deaths occurring at 20-27 weeks of gestation was 2.89, a 4% increase from 2022 (2.79). For deaths occurring at 28 weeks of gestation or more, the rate in 2023 (2.66) was not significantly different from 2022 (2.71). In 2023, the fetal mortality rate was highest for Native Hawaiian or Other Pacific Islander non-Hispanic (10.18) and Black non-Hispanic (9.95) women and lowest for Asian non-Hispanic women (4.14). Fetal mortality rates were highest for females younger than 15 and age 40 and older, for women who smoked during pregnancy, and for women with multiple gestation pregnancies. Five selected causes accounted for 89.9% of fetal deaths in the 38-state and District of Columbia reporting area.

PMID:40712060 | DOI:10.15620/cdc/174593

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Sex Differences in Disc Golf Performance: Implications for Eligibility Criteria for Women’s Competitions

Eur J Sport Sci. 2025 Aug;25(8):e70008. doi: 10.1002/ejsc.70008.

ABSTRACT

Disc golf is becoming increasingly popular, but there is no published information on performance differences between males and females. The aim of this study was to investigate sex differences in disc golf performance in recent years and to discuss the implications of these sex differences on eligibility criteria for women’s disc golf competitions. We used publicly available data sources from the Professional Disc Golf Association (PDGA) and Disc Golf Pro Tour (DGPT) to compile performance data related to player ratings, throwing distance, throwing accuracy, and putting success at the professional, amateur, and junior levels. In the Pro class (n = 16,843), the median male player rating was 936 compared with 851 for females (P < 0.001). In the amateurs, over 5000 males had a higher rating than the best female player. In throwing for distance, males threw 23%-54% further than females (P < 0.001). Differences in accuracy were smaller but significant, with males outperforming females in measures of throwing accuracy in the Pro class (average 70.9% vs. 63.4% fairway hits; P < 0.001) and putting consistency (median 82% vs. 69%; P < 0.001). In junior competitions, boys showed higher ratings and better performance than girls, with clear differences already observed at age 10 (e.g., median rating 775 vs. 529; P < 0.001). In conclusion, male disc golfers outperformed female players in player rating, throwing distance, and accuracy in the professional, amateur, and junior divisions. Disc golf governing bodies struggling with setting eligibility criteria for women’s disc golf competitions may use these results to better inform policy.

PMID:40712057 | DOI:10.1002/ejsc.70008

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Data Briefs

NCHS Data Brief. 2025 Jul;(530):1. doi: 10.15620/cdc/174602.

ABSTRACT

OBJECTIVES: This report describes changes from 2022 to 2023 in the perinatal mortality rate, overall, by its components, and by mother’s age, race and Hispanic-origin, and state.

METHODS: This report is based on data from the Fetal Death Data File and the Linked Birth/Infant Death Data File from the National Vital Statistics System (NVSS). This report uses an expanded measure of perinatal mortality, which includes all fetal deaths at 20 completed weeks or more and infant deaths younger than age 7 days. The differences between rates noted in the text are statistically significant at the 0.05 level unless otherwise noted.

KEY FINDINGS: The U.S. perinatal mortality rate was 8.36 perinatal deaths per 1,000 live births and fetal deaths in 2023, a nonsignificant change from the rate of 8.27 in 2022. The early fetal mortality rate increased by 4%, from 2.79 in 2022 to 2.89 in 2023; changes in late fetal and early neonatal mortality were not significant. Increases in the perinatal mortality rate were seen for women younger than age 20, Hispanic females, and in three states (Alabama, Colorado, and New Jersey); a decline was seen in one state (Michigan). Changes for other groups were not significant.

PMID:40712056 | DOI:10.15620/cdc/174602

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National Vital Statistics Reports

Natl Vital Stat Rep. 2025 Jun 10;(4):1. doi: 10.15620/cdc/174588.

ABSTRACT

OBJECTIVES: This report presents final 2022 data on U.S. deaths, death rates, life expectancy, infant and maternal mortality, and trends by selected characteristics such as age, sex, Hispanic origin and race, state of residence, and cause of death.

METHODS: Information reported on death certificates is presented in descriptive tabulations. The original records are filed in state registration offices. Statistical information is compiled in a national database through the Vital Statistics Cooperative Program of the National Center for Health Statistics. Causes of death are processed according to the International Classification of Diseases, 10th Revision . Beginning in 2018, all states and the District of Columbia were using the 2003 revised certificate of death for the entire year, which includes the 1997 Office of Management and Budget revised standards for race. Data based on these revised standards are not completely comparable to previous years.

RESULTS: In 2022, a total of 3,279,857 deaths were reported in the United States. The age-adjusted death rate was 798.8 deaths per 100,000 U.S. standard population, a decrease of 9.2% from the 2021 rate. Life expectancy at birth was 77.5 years, an increase of 1.1 years from 2021. Age-specific death rates decreased from 2021 to 2022 for age groups 15-24, 25-34, 35-44, 45-54, 55-64, 65-74, 75-84, and 85 and older and increased for age groups 1-4 and 5-14. In 2022, the 10 leading causes of death remained the same as in 2021, although four causes changed rank. Heart disease remained the top leading cause, followed by cancer. The infant mortality rate, 5.60 deaths per 1,000 live births in 2022, increased 2.9% from the rate in 2021 (5.44).

CONCLUSIONS: In 2022, the age-adjusted death rate decreased and life expectancy at birth increased for the total, male, and female populations, primarily due to the decrease in deaths from COVID-19.

PMID:40712053 | DOI:10.15620/cdc/174588

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Statistical Superiority Without Clinical Relevance: A Critical Appraisal of Recent HA Filler Studies

Aesthet Surg J. 2025 Jul 25:sjaf139. doi: 10.1093/asj/sjaf139. Online ahead of print.

NO ABSTRACT

PMID:40712045 | DOI:10.1093/asj/sjaf139

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Local recurrence after sublobar resection for primary lung cancer: Does the type of stapling device matter?

Interdiscip Cardiovasc Thorac Surg. 2025 Jul 25:ivaf171. doi: 10.1093/icvts/ivaf171. Online ahead of print.

ABSTRACT

OBJECTIVES: Two major types of stapling devices exist: those with disposable built-in knives and those with non-disposable built-in knives. This study investigated whether the stapler type influences the incidence of local recurrence, including margin recurrence and pleural dissemination, after curative sublobar resection for lung cancer.

METHODS: We retrospectively reviewed patients who underwent sublobar resection at our institution between 2010 and 2021. We compared disease-free survival, overall survival, and local recurrence between procedures using a stapler with a disposable knife and those using a stapler with a non-disposable knife.

RESULTS: A total of 269 patients were included: 84 were treated with the disposable-knife stapler and 185 with the non-disposable-knife stapler. Local recurrence occurred in 22 of 269 patients (8.2%), including 9 of 84 (10.7%) in the disposable group and 13 of 185 (7.0%) in the non-disposable group (p = 0.72). Patients who developed local recurrence tended to be older, male, have a smoking history, squamous cell carcinoma, absence of a ground-glass component, positive stapling cartridge cytology, partial resection, right lower lobe tumors, elevated carcinoembryonic antigen, and higher maximum standardized uptake values. In a propensity score-matched study (78 patients per group), no significant differences in disease-free survival, overall survival, or local recurrence were detected between the stapler types.

CONCLUSIONS: No statistically significant differences in oncological outcomes were observed between stapler types in this retrospective study; however, the absence of a significant difference does not rule out a real effect. Further large-scale research is warranted. (247words).

PMID:40712002 | DOI:10.1093/icvts/ivaf171

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Peri-implant Tissue Changes Around Maxillary Anterior Immediate Tooth Replacement With and Without Socket- Shield: 1-Year Randomized Controlled Clinical Trial

Int J Oral Maxillofac Implants. 2025 Jul 25;40(4):459-467. doi: 10.11607/jomi.11308.

ABSTRACT

PURPOSE: To evaluate implant success rates and facial mucosal profile changes in maxillary single immediate implant placement and provisionalization with the socket-shield (IIPP+SS) technique and without the socket-shield (IIPP-SS) technique.

MATERIALS AND METHODS: A total of 30 dental implants in 25 patients were assigned to either the IIPP-SS group (15 implants) or the IIPP+SS (15 implants) group. Clinical and radiographic outcomes were collected preoperatively (T0) as well as at 2-week (T1), 6-month (T6), and 12-month (T12) postoperative follow-ups. The implant success rate, marginal bone level changes, facial mucosal level changes, and papilla level changes were evaluated at different time points. Facial mucosal profile changes were assessed individually for hard and soft tissue zones and as a whole using volumetric analysis.

RESULTS: Two implants were excluded (one patient dropped out and one implant failed) from the data analysis in this study, resulting in an overall implant success rate of 96.6% (28/29) after 1 year. Fewer facial mucosal profile changes were noted in the IIPP+SS group than in the IIPP-SS group; however, the difference was only marginally statistically significant (P = .06). No statistically significant difference was found in the facial mucosal level changes (P = .18) and papilla level changes (P = .67 for the mesial papilla level, P = .41 for the distal papilla level) between the IIPP-SS and IIPP+SS groups.

CONCLUSIONS: Within the limitations of this 1-year randomized controlled clinical trial, the IIPP+SS group appeared to maintain the implant facial mucosal profile slightly better than IIPP alone. Both treatment modalities provide clinically satisfactory outcomes biologically, functionally, and esthetically.

PMID:40711987 | DOI:10.11607/jomi.11308