Tag: nevin manimala

Cell Tissue Bank. 2026 Apr 22;27(2):23. doi: 10.1007/s10561-026-10223-5.

ABSTRACT

This study assessed pregnant women’s awareness and attitudes toward umbilical cord blood donation and banking, and identified independent factors associated with awareness. This study was conducted in Gaziantep Province, Turkey, between March and June 2025, using a descriptive, cross-sectional design involving 204 pregnant women. Participants were recruited using a non-probability convenience sampling method. Data were collected via an online questionnaire that assessed socio-demographic characteristics and knowledge and attitudes towards umbilical cord blood donation and banking. Awareness levels were categorized as “no knowledge”, “limited knowledge”, and “sufficient knowledge”, and dichotomized as “insufficient” versus “partial/sufficient” for regression analysis. Descriptive statistics and the Chi-square test were used to analyze the data. In addition to descriptive statistics, binary logistic regression analysis was performed to identify independent factors associated with awareness of umbilical cord blood donation and banking. Statistical significance was set at p < 0.05. The average age of the pregnant women was 30.38 ± 4.48. Only 3.9% had sufficient knowledge about UCB donation and banking, while the majority (96.1%) had never received any information about UCB donation, and none had ever donated before. The main reason for not donating was a lack of information (89.7%). The income and education level of the pregnant women were significantly associated with their knowledge and attitudes towards UCB donation and banking (p < 0.05). A family history of disease positively influenced knowledge and attitudes (p < 0.05), whereas religious beliefs negatively influenced donation intentions. Again, most pregnant women (79.9%) stated that they wanted to receive education about UCB donation and banking. Binary logistic regression analysis identified education level as the strongest independent predictor of awareness. In light of these findings, education on UCB donation and banking should be included in prenatal care processes. Involving women, families, and communities in awareness-raising initiatives can increase knowledge and participation in donation programmes.

PMID:42018221 | DOI:10.1007/s10561-026-10223-5

Eur Radiol. 2026 Apr 22. doi: 10.1007/s00330-026-12551-2. Online ahead of print.

NO ABSTRACT

PMID:42018184 | DOI:10.1007/s00330-026-12551-2

Eur Radiol. 2026 Apr 22. doi: 10.1007/s00330-026-12541-4. Online ahead of print.

NO ABSTRACT

PMID:42018183 | DOI:10.1007/s00330-026-12541-4

Eur Radiol. 2026 Apr 22. doi: 10.1007/s00330-026-12552-1. Online ahead of print.

NO ABSTRACT

PMID:42018182 | DOI:10.1007/s00330-026-12552-1

Eur Radiol. 2026 Apr 22. doi: 10.1007/s00330-026-12542-3. Online ahead of print.

NO ABSTRACT

PMID:42018181 | DOI:10.1007/s00330-026-12542-3

Tech Coloproctol. 2026 Apr 22. doi: 10.1007/s10151-026-03304-w. Online ahead of print.

ABSTRACT

BACKGROUND: Early age at diagnosis in Crohn’s disease is linked to aggressive phenotypes, yet evidence regarding its impact on surgical risk remains inconsistent. This study aimed to elucidate the relationship between age at diagnosis, utilizing Vienna and Montreal classifications, and surgical prognosis in patients undergoing ileocecal resection.

METHODS: A retrospective analysis of a prospective database identified 810 patients undergoing ileocecal resection between 2014 and 2022. Patients were stratified by Vienna (< 40 versus > 40 years) and Montreal (A1, A2, A3) classifications. Primary end points included 30-day overall complications, serious complications, reoperation and readmission. Statistical analysis employed multivariable regression, propensity score matching, G-computation and Random Forest models to adjust for confounders.

RESULTS: Baseline characteristics differed significantly: younger patients exhibited more penetrating disease and biologic exposure, while older patients had higher ASA scores and comorbidities. After robust adjustment, the Vienna and Montreal age classification showed no significant association with postoperative complications, serious complications, reoperation or readmission. Random Forest analysis consistently identified ASA score and comorbidities, rather than age at onset, as the dominant predictors of surgical outcomes.

CONCLUSIONS: Age at diagnosis does not independently predict short-term surgical outcomes after ileocecal resection. Postoperative morbidity is driven primarily by general health markers, such as ASA score, rather than disease onset timing. These findings highlight the need for validated disease-specific risk scores.

PMID:42018163 | DOI:10.1007/s10151-026-03304-w

Eur J Pediatr. 2026 Apr 22;185(5):288. doi: 10.1007/s00431-026-06930-6.

ABSTRACT

The rapid rise of short video consumption among children and adolescents has raised concerns regarding its associations with cognitive and emotional functioning. This study aimed to examine whether cognitive emotion regulation strategies predict short video addiction levels in children aged 10-14 and to explore the relationship between specific emotion regulation strategies and short video addiction. A descriptive and correlational research design was employed. The study was conducted between January and June 2025 with 202 middle school students aged 10-14. Participants completed an Information Form, the Short Video Addiction Scale (SVAS), and the Turkish Child Version of the Cognitive Emotion Regulation Questionnaire (CERQ-k). Descriptive statistics, correlation analyses, and multiple linear regression analyses were performed. The mean age of the participants was 12.12 years (SD = 1.24). Most were female (52.97%) and enrolled in the 7th grade (30.20%). SVAS scores were positively correlated with self-blame (r = .21, p < .05), putting into perspective (r = .20, p < .05), and catastrophizing (r = .24, p < .01), indicating that higher levels of short video addiction were associated with greater reliance on maladaptive cognitive emotion regulation strategies. Regression analysis identified catastrophizing as a significant predictor of short video addiction scores (B = 0.59, p < .05), indicating that greater use of catastrophizing was associated with higher levels of short video addiction.

CONCLUSION: The findings indicate that maladaptive cognitive emotion regulation strategies, particularly self-blame and catastrophizing, are associated with higher levels of short video addiction among children. These results highlight the importance of interventions that strengthen adaptive emotion regulation skills as a potential approach to preventing or reducing problematic short video use in childhood.

WHAT IS KNOWN: • Short video use is increasingly common among children and may be associated with cognitive and emotional functioning. • Maladaptive cognitive emotion regulation strategies, such as self-blame and catastrophizing, are linked to poorer emotional and behavioral outcomes in children.

WHAT IS NEW: • Maladaptive cognitive emotion regulation strategies are associated with higher levels of short video addiction in children aged 10-14. • Catastrophizing significantly predicts short video addiction, identifying a potential target for early prevention and intervention efforts.

PMID:42018161 | DOI:10.1007/s00431-026-06930-6

Diabetologia. 2026 Apr 22. doi: 10.1007/s00125-026-06740-3. Online ahead of print.

ABSTRACT

AIMS/HYPOTHESIS: Ethnic disparities in the incidence of type 2 diabetes mellitus are well documented in multiethnic urban populations, but the contributions of migration status and mental health are less well understood. This study used a large dataset from primary care centres in South London that is unique in that it includes migration-related information together with information on mental and physical health comorbidities. We aimed to assess how migration status and mental health contribute to longitudinal associations of ethnicity and type 2 diabetes risk in a multiethnic urban population.

METHODS: We conducted a longitudinal cohort study (2012-2019) of approximately 340,000 adults without baseline type 2 diabetes. Cox proportional hazards models were applied with sequential adjustments: first for age and sex; second, adding migration status (country of birth being UK or not); and third, further adding mental health conditions (depression, anxiety, severe mental illness), physical health factors (BMI, hypertension and other macrovascular diseases) and area-level deprivation. This approach allowed us to examine whether ethnic differences in the incidence of type 2 diabetes persist after accounting for additional factors.

RESULTS: South Asian, Black African and Black Caribbean groups had 2-3-fold higher type 2 diabetes risks compared with White British individuals, which were only partially explained by socioeconomic and clinical factors. Being born outside the UK increased type 2 diabetes risk by 29% across all ethnic groups. Depression/anxiety and severe mental illness were associated with a higher risk of type 2 diabetes. No statistical evidence of strong interactions between these factors was obtained.

CONCLUSIONS/INTERPRETATION: Ethnicity, migration status and mental health conditions were each independently associated with type 2 diabetes risk, and ethnic disparities persisted after adjustment. The lack of evidence for interactions suggests that migration- and mental health-related mechanisms may operate similarly across ethnic groups rather than amplifying or mitigating existing disparities in type 2 diabetes rates. Efforts to reduce diabetes inequalities will require both support for post‑migration challenges and addressing of the broader structural and environmental determinants underlying persistent ethnic disparities.

PMID:42018145 | DOI:10.1007/s00125-026-06740-3

Equine Vet J. 2026 Apr 22. doi: 10.1002/evj.70170. Online ahead of print.

ABSTRACT

BACKGROUND: Misconceptions can be defined as ‘false, persistent beliefs’ or ‘inaccurate, prior knowledge’ and can influence decision-making.

OBJECTIVES: To investigate the impact of evidence-based information on UK horse owners’ decision-making for colic.

STUDY DESIGN: Mixed-methods cross-sectional study.

METHODS: An online survey was distributed to UK horse owners, with four sections: owner demographics; views on decision-making and referral to an equine hospital facility for colic; current knowledge and approach to colic; impact of evidence-based information (including evidence on recognising and responding to colic, and colic surgery survival and outcome data) on decision-making. Statistical analysis was performed using Kendall’s tau for continuous variables and Chi-squared testing for categorical variables. Multivariable analysis was performed using a generalised linear model with binomial distribution (logistic regression), with p < 0.05 for model fit. Content analysis was used for free-text answers.

RESULTS: In total, 1544 participants met inclusion criteria. Owners were more likely to agree to referral if their horse was insured (p < 0.001, 95% confidence interval [CI]: 1.86-2.93), and less likely if their horse was older (p < 0.001, CI: 0.90-0.94) or they felt pressure (p < 0.001, CI: 0.44-0.70). Pressure to refer was mainly from veterinary professionals (66%, 367/549) or peers (20%, 110/549). Many participants were unaware of how quickly irreversible intestinal damage could occur (58%, 903/1544), costs of colic surgery and UK insurance cover limits (63%, 966/1544), post-operative survival rates for geriatric vs. non-geriatric horses (65%; 996/1544), or prognosis for return to work following colic surgery (68%, 1052/1544). Sharing evidence-based information had limited impact on decision-making. Free text response analysis identified previous experience of colic, anecdotal information, finances and peer pressures as barriers to change.

MAIN LIMITATIONS: Potential for response bias, UK participants only.

CONCLUSIONS: Misconceptions around colic were common, with many horse owners reluctant to change their approach after evidence-based information. Intent to pursue referral was less likely with increasing horse age and perceived pressure to refer.

PMID:42018127 | DOI:10.1002/evj.70170

Eur J Health Econ. 2026 Apr 22. doi: 10.1007/s10198-026-01923-6. Online ahead of print.

NO ABSTRACT

PMID:42018119 | DOI:10.1007/s10198-026-01923-6