Arch Esp Urol. 2022 Dec;75(10):867-872. doi: 10.56434/j.arch.esp.urol.20227510.126.
ABSTRACT
BACKGROUND: To investigate the influencing factors of health-related quality of life (HRQOL) in children and adolescents with congenital adrenal hyperplasia (CAH).
METHODS: Pediatric Quality of Life Inventory 4.0 (PedsQL4.0) and 8-item Morisky medication adherence scale (MMAS-8) were used to survey eighty-seven children and adolescents with CAH (5-18 years), as well as their parents. SPSS 26.0 software was utilized for statistical analysis.
RESULTS: The scores of social functions, school performance, social psychological function and total scores of CAH girls aged 13-18 years were lower than those of boys (p < 0.05). CAH children with older age, longer course of disease, older than 3 years old at first diagnosis, living in rural areas, lower education level of caregivers and lower family monthly income had lower scores. CAH patients with poor compliance and complications had significantly lower scores in each single domain, social psychological function, and total scores than those with good compliance and no complications (p < 0.05).
CONCLUSIONS: Age, age at initial diagnosis, course of disease, complications, compliance, residence, education level of caregivers and family income were important factors affecting HRQOL of CAH children and adolescents, among which complications and compliance were independent key influencing factors.
PMID:36651098 | DOI:10.56434/j.arch.esp.urol.20227510.126
