Nevin Manimala

J Nurs Manag. 2026;2026(1):e3543130. doi: 10.1155/jonm/3543130.

ABSTRACT

BACKGROUND: Problematic mobile phone use is an emerging public health issue, the prevalence of which has increased among nurses.

AIM: To synthesize and describe knowledge on problematic mobile phone use by nurses, its consequences, and strategies for addressing this phenomenon.

DESIGN: A systematic review was conducted following the checklist Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement. This systematic review has been registered in PROSPERO (CRD420251052591).

METHODS: Four electronic databases were systematically searched from their inception to September 2025. The article’s reference lists were also manually searched. The study selection was carried out in three stages, with two reviewers independently analyzing the data and resolving disagreements. The quality assessment utilized the Mixed Method Appraisal Tool, considering the criteria established for each study design.

RESULTS: Sixteen studies from four online databases were selected, the majority of which were cross-sectional and descriptive. The risk factors for problematic mobile phone use, the negative consequences for mental and physical health, and the clinical work of nurses were highlighted, such as a combination of strategies to prevent and mitigate problematic mobile phone use in the clinical setting.

CONCLUSION: The problematic mobile phone use of nurses negatively affects their mental and physical health, as well as their performance in the clinical setting.

IMPLICATION FOR NURSING MANAGEMENT: The findings of this study may inform the need for nursing managers to develop and implement strategies to prevent and mitigate the problematic use of these devices among nurses and ensure the appropriate use of mobile phones in the clinical setting.

PMID:41873504 | DOI:10.1155/jonm/3543130

Hum Vaccin Immunother. 2026 Dec;22(1):2633892. doi: 10.1080/21645515.2026.2633892. Epub 2026 Mar 24.

ABSTRACT

As life expectancy increases, age-related diseases become more frequent and severe, making vaccination a key strategy for disease prevention. To assess the knowledge and attitudes toward herpes zoster and to determine associations with acceptability of vaccination among patients and dermatologists, a descriptive and quantitative analytic cross-sectional survey-based study was conducted among patients aged ≥50 y in a tertiary hospital, and dermatologists in the Philippines. Majority of dermatologists had good knowledge (97.5%) and attitudes (99.7%) toward vaccination. Reported barriers were vaccine cost, procurement, and storage. Only 32.8% of patients were aware of herpes zoster, of which 61.7% had good knowledge and 99.2% had positive attitudes toward vaccination. Majority (87.0%) were willing to be vaccinated. Fear of side effects and unwillingness to pay limited acceptance. Knowledge did not impact vaccine acceptance, but favorable attitudes were associated with acceptance in both groups. Recall and social desirability bias cannot be ruled out, and sampling of patients was limited to a single outpatient clinic. Overall, Filipino dermatologists exhibit high levels of knowledge, positive attitudes, and vaccine acceptability. While patient awareness was limited, vaccine acceptability is high, particularly when recommended by a physician, highlighting their critical role in primary care.

PMID:41873494 | DOI:10.1080/21645515.2026.2633892

Future Microbiol. 2026 Mar 24:1-7. doi: 10.1080/17460913.2026.2645506. Online ahead of print.

ABSTRACT

Vaccination programs have averted millions of childhood deaths, yet vaccine-preventable diseases (VPDs) continue to resurge as coverage declines and pathogen evolution undermines previously successful vaccines. Anticipating resurgence is a public health priority. We review theoretical and empirical advances in the study of early warning signals (EWS) of epidemic transitions, with a focus on critical slowing down (CSD) – a phenomenon in which recovery from perturbations becomes slower near the epidemic threshold. We summarize the mechanisms that generate CSD, indicators that can be extracted from surveillance data, and the conditions under which signals may be detectable. We then examine case studies to illustrate the opportunities and challenges of applying EWS to VPD resurgence. Theory and computer simulations show that CSD can precede both elimination and resurgence, with increases in variance and autocorrelation calculated from disease surveillance reports emerging as consistent indicators. Empirical evidence supports this potential, though performance depends on noise structure, seasonality, spatial clustering, and outbreak responses. Case studies highlight both successful applications and contexts where signals were weak or absent. EWS offer a promising framework for anticipating VPD resurgence, but further research is required to refine methods, integrate mechanistic and social-behavioral drivers, and evaluate applicability across pathogens and settings.

PMID:41873479 | DOI:10.1080/17460913.2026.2645506

Cephalalgia. 2026 Mar;46(3):3331024261431339. doi: 10.1177/03331024261431339. Epub 2026 Mar 24.

ABSTRACT

AimHeadaches are a common complaint among children and adolescents, with prevalence rising over the past decades. This study aimed to retrospectively analyze all emergency consultations presenting with headache as the primary symptom at a Level 1 Pediatric Emergency Department (PED) over 7 years, encompassing the COVID-19 pandemic.MethodsAll electronic health records (EHR) of patients aged 2 to 18 years who presented to the PED with non-traumatic headache between January 2018 and December 2024 were retrospectively reviewed. In addition to primary headache diagnoses, conditions commonly associated with headaches were included to identify relevant emergency department cases. Statistical analyses included the chi-square test or Fishers exact test, calculation of Odds Ratios and ANOVA, significant at p < 0.05.ResultsA total of 1278 children and adolescents (564 males, 44.1%; 714 females, 55.9%) with acute headaches visited our PED 1447 times. Of those patients, 668 (46.2%) were diagnosed with primary headaches, 677 (46.8%) with secondary headaches, five (0.3%) with cranial neuropathies and facial pain, and 97 (6.7%) had headaches that could not be clearly classified. Acute headache cases accounted for 3.6% of all PED visits. The largest relative increase compared to the baseline year (2018) was observed in 2023 (+36.2%). Immediate neuroimaging was performed in 19.1% of cases. Red flag symptoms, including systemic symptoms with fever, neoplasm in history, progressive headache, headache associated with severe vomiting and papilledema, were significantly associated with abnormal brain MRI findings. Pharmacological analgesic therapy was administered in 31.9% of cases, and pain assessment was recorded in 46.1% of cases.ConclusionVisits to the PED for headaches are increasing, particularly following the COVID-19 pandemic. The high prevalence of primary headache diagnoses, combined with still insufficient pain management, highlights the need for enhanced education for both pediatricians and parents. For secondary headaches, a thorough headache history focusing on all red flag symptoms, along with a detailed neurological examination assessing clinical features, should form the basis for deciding whether immediate neuroimaging is necessary.Trial registrationThe study has also been officially registered on the public webpage of the German Clinical Trials Registry (GermanCTR) at https://drks.de/search/en/trial/DRKS00036917 (Clinical Trial Number/ DRKS-ID: DRKS00036917, Date of Registration: 2025-05-16, last update: 2025-07-28, registration type: retrospective, status: recruiting complete, study complete).

PMID:41873465 | DOI:10.1177/03331024261431339

Ann Med. 2026 Dec;58(1):2637271. doi: 10.1080/07853890.2026.2637271. Epub 2026 Mar 24.

ABSTRACT

BACKGROUND: To evaluate the association between albumin administration as volume replacement and mortality in adult ARDS patients, we performed this meta-analysis and trial sequential analysis (TSA).

METHODS: We searched databases including PubMed, Science Direct, Scopus, Web of Science databases and Cochrane Central Register of Controlled Trials up to 12 December 2024. We screened trials that included adult ARDS patients and compared albumin with crystalloid. The 28-day mortality served as the primary endpoint, while the oxygenation change, the length of ICU stay and the length of hospital stay were designated as secondary outcomes. To clarify the differing concentrations of albumin, we formed two distinct subgroups: the hyper-oncotic albumin subgroup (≥20%) and the iso-oncotic albumin subgroup (4%∼5%). Statistical synthesis was performed with Cochrane Review Manager 5.4.1, employing random-effects models. To mitigate random errors, TSA was implemented with α = 0.05 and β = 0.20 parameters.

RESULTS: The analysis incorporated 5 publications: 3 randomized controlled trials (RCTs) and 2 non-randomized studies (NRSs). Overall mortality was lower in the albumin group (33.2%, 97/292) than in the crystalloid group (44.9%, 133/296) (OR = 0.61, 95%CI 0.43-0.85, p = 0.004). RCTs (n = 204) showed no benefit (OR = 0.83, p = 0.54), but NRSs (n = 384) demonstrated reduced mortality (OR = 0.52, p = 0.002). Hyper-oncotic albumin was associated with lower mortality in NRSs (OR = 0.40, p = 0.02) but not in RCTs (OR = 0.74, p = 0.57). Iso-oncotic albumin showed no benefit (OR = 0.88, p = 0.72). Regarding the impact of albumin on oxygenation, significant improvements in oxygenation were observed only on the first (p = 0.05) and second days (p < 0.0001). The TSA indicated a continued need for high-quality RCTs.

CONCLUSIONS: Our analysis suggests that hyper-oncotic albumin may reduce mortality and improve early oxygenation in ARDS patients compared to crystalloids. Larger RCTs are urgently needed to validate these findings and define their potential role in clinical management.

PMID:41873460 | DOI:10.1080/07853890.2026.2637271

Clin Cosmet Investig Dermatol. 2026 Mar 18;19:586105. doi: 10.2147/CCID.S586105. eCollection 2026.

ABSTRACT

BACKGROUND: Horizontal neck lines are an early and conspicuous marker of cutaneous aging. Intradermal hyaluronic acid (HA) injections have become a standard minimally invasive countermeasure, yet comparative data for composite HA solutions in Asian populations remain scarce.

PURPOSE: To evaluate the efficacy and safety of injectable sodium hyaluronate composite solution (NCTF^® 135 HA) compared with injectable sodium hyaluronate composite solution (HEARTY^®) for the correction of moderate-to-severe neck wrinkles.

METHODS: In this prospective, multicenter, randomized, evaluator-blinded, active-controlled, non-inferiority trial, 188 subjects with moderate-to-severe neck wrinkles were randomly assigned (1:1) to the experimental group or the control group, with both groups receiving three sessions of non-cross-linked injectable sodium hyaluronate composite solution at 4-week intervals. Improvement of Allergan Transverse Neck Lines Scale (ATNLS), subject-assessed Global Aesthetic Improvement Scale (GAIS) and adverse events (AEs) were evaluated and compared before the 3 injection sessions and at 4, 12, and 24 weeks post-final injection.

RESULTS: At week 4 post-final injection, the ATNLS response rates were 88.30% in the experimental group and 85.11% in the control group, respectively, with a between-group difference of 3.19% (95% confidence interval (CI): [-0.0723, 0.0987], p = 0.5410), demonstrating non-inferiority of the experimental treatment to the active control. Among the secondary endpoints, neither ATNLS response rates at additional time points nor subject-assessed GAIS responder rates showed statistically significant differences between groups. A total of 128 adverse events were reported, with no statistically significant difference between groups: 26 (27.66%) in the experimental group and 38 (40.43%) in the control group. No device- or procedure-related serious adverse events occurred.

CONCLUSION: Injectable sodium hyaluronate composite solution (non-cross-linked) provides safe, effective, and non-inferior correction of moderate-to-severe neck wrinkles compared with active control, expanding minimally invasive therapeutic options for cervical rejuvenation.

PMID:41873431 | PMC:PMC13005982 | DOI:10.2147/CCID.S586105

PeerJ. 2026 Mar 19;14:e20867. doi: 10.7717/peerj.20867. eCollection 2026.

ABSTRACT

BACKGROUND: Previous research suggests a possible relationship between physical activity and cognitive functioning in children. However, the findings remain inconsistent, and few studies have examined this link using standardized instruments in preadolescent populations. This study aimed to determine the association between self-reported physical activity and cognitive performance in 10-11-year-old school children.

METHODS: A total of 423 children (213 girls and 210 boys; 10.66 ± 0.43 years) participated in this study. The level of physical activity was assessed using the Physical Activity Questionnaire for Children (PAQ-C), while cognitive performance was measured with the d2-R Test of Attention. Data were analyzed using Pearson correlations and a multivariate general linear model (GLM).

RESULTS: Statistically significant correlations were found between PAQ-C scores and two d2-R variables, the total number of items processed (PRZ) and concentration performance (VS), whereas the association with percentage of errors (Ch%) was not significant. The multivariate GLM confirmed these patterns: PAQ-C was significantly associated with PRZ (β = 2.596, p = 0.003) and VS (β = 1.973, p = 0.012), but not with Ch% (p = 0.281). Gender was also a significant predictor of PRZ and VS.

CONCLUSION: Self-reported physical activity showed small but statistically significant associations with selected attention outcomes, particularly processing speed and concentration. Given the cross-sectional design and reliance on self-report, causal inference is not possible; however, these findings highlight the potential relevance of physical activity for attentional functioning in school settings and underscore the need for longitudinal and intervention-based research.

PMID:41873424 | PMC:PMC13006003 | DOI:10.7717/peerj.20867

Cancer Med. 2026 Mar;15(3):e71635. doi: 10.1002/cam4.71635.

ABSTRACT

BACKGROUND: In China, the incidence and burden of pediatric neoplasms have been increasing, contributing to escalating healthcare expenditures and productivity losses, with hospitalization costs constituting a major component of the economic burden. However, evidence on the full spectrum of neoplasm-related hospitalization costs for pediatric patients remains limited, particularly from real-world longitudinal studies.

METHODS: This retrospective multicenter cohort study (2017-2023) analyzed pediatric hospitalization data in Shanghai by integrating data from two administrative databases. The study included all children aged ≤ 18 years hospitalized with ICD-10-coded benign and malignant neoplasms and related complications. Hospitalization costs were discounted to 2023 values, converted to US dollars, and analyzed using descriptive statistics and generalized linear models (GLMs) to identify influencing factors, including socioeconomic, clinical, and hospital-related variables.

RESULTS: Among 688,131 pediatric hospitalizations, 13,057 (1.91%) were for neoplasms. Neoplasm patients had significantly higher care intensity and hospitalization costs than nonneoplasm patients, with malignant neoplasms incurring the highest median costs. From 2017 to 2023, total costs for neoplasm patients declined by 26.88%, driven by a 52.87% reduction in drug costs, contrasting with rising costs for nonneoplasm patients. Leukemia was the most prevalent condition, while some rare but high-cost entities, such as secondary malignant neoplasms of the respiratory and digestive organs, were among the most expensive. GLM analysis identified sex, insurance type, pathology, surgical interventions, length of stay, and hospital characteristics as significant cost drivers.

CONCLUSION: This study provides comprehensive evidence on hospitalization cost patterns, trends, and influencing factors for pediatric neoplasms. It highlights the need for enhanced insurance coverage, early diagnosis and treatment, and equitable resource allocation to reduce disparities.

PMID:41872103 | DOI:10.1002/cam4.71635

Clin Pediatr (Phila). 2026 Mar 23:99228261431967. doi: 10.1177/00099228261431967. Online ahead of print.

ABSTRACT

The aim of this study was to examine the effect of inspiratory muscle training (IMT) on respiratory functions, balance, and functional capacity in trainable children with intellectual disabilities. Thirty children aged between 8 and 17 years, diagnosed with trainable intellectual disabilities, were randomly assigned to either an experimental group (IMT) or control (conventional physiotherapy) group (5 days/week/8 weeks). Spirometry, 6-minute walk test (6MWT), and the Berg Balance Scale (BBS) were used for assessment. There were significant main effects of time and time × group interaction on 6MWT, predicted 6MWT, BBS, forced expiratory volume in 1 second (FEV₁), forced expiratory volume in 1 second (percentage of predicted) (FEV₁%), forced vital capacity (FVC), forced vital capacity (percentage of predicted), and maximal expiratory pressure (percentage of predicted (MEP%) in the experimental and control groups (P < .05). There was a statistically significant main effect of time on FEV₁/FVC, maximal inspiratory pressure, maximal inspiratory pressure (percentage of predicted), and MEP values (P < .05), with no significant group or interaction effects. Inspiratory muscle training is a feasible and effective intervention for individuals with intellectual disabilities, aiming to improve their respiratory function, functional capacity, and balance.

PMID:41872065 | DOI:10.1177/00099228261431967

Musculoskeletal Care. 2026 Mar;24(1):e70209. doi: 10.1002/msc.70209.

ABSTRACT

OBJECTIVE: To explore associations between the presence and severity of diastasis of the rectus abdominis muscles (DRAM) and common postpartum musculoskeletal complaints in the first 2 years postpartum.

STUDY DESIGN: Cross-sectional survey among women within 2 years of childbirth.

BACKGROUND: DRAM commonly affects women during pregnancy and postpartum, but its relationship with musculoskeletal complaints remains unclear. This study investigates the association between DRAM and postpartum musculoskeletal complaints, including low back pain, pelvic girdle pain, abdominal pain, and pelvic floor dysfunction.

METHODS AND MEASURES: Participants were identified from medical records of women who had delivered a baby in the previous 2 years at Southwest Healthcare, Warrnambool, Victoria, Australia. An electronic questionnaire collected data on DRAM presence and severity (self-reported based on self-assessment or prior healthcare professional screening), musculoskeletal complaints, and pelvic floor dysfunction both currently (within the past week) and early postpartum (within the first 3 months). Statistical univariate and multivariate regression analyses explored associations between DRAM presence or severity and reported symptoms adjusted for age, parity, delivery method and time since last delivery.

RESULTS: Of 177 respondents (from 785 survey invitations), 38% (n = 70) reported DRAM. In multivariate analysis, DRAM presence was significantly associated with current (p = 0.034) and early postpartum (p = 0.037) abdominal discomfort, and urinary urgency symptoms early postpartum (p = 0.033). No significant associations were found between DRAM and low back pain, pelvic girdle pain, or stress urinary incontinence.

CONCLUSION: DRAM was weakly associated with abdominal discomfort and urinary urgency symptoms but not with other musculoskeletal complaints. These findings align with limited previous research on this topic. More data are needed to explore the association between DRAM severity and musculoskeletal disorders.

PMID:41872055 | DOI:10.1002/msc.70209