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Nevin Manimala Statistics

Patient Safety/Quality Improvement Primer, Part IV: How to Measure and Track Improvements

Otolaryngol Head Neck Surg. 2023 Jul 20. doi: 10.1002/ohn.430. Online ahead of print.

ABSTRACT

Patient safety and quality improvement (PS/QI) has become an integral part of the health care system, and the ability to effectively use data to track, understand, and communicate performance is essential to designing and implementing quality initiatives, as well as assessing their impact. Though many otolaryngologists are proficient in the methodologies of traditional research pursuits, educational gaps remain in the foundational principles of PS/QI measurement strategies. Part IV of this PS/QI primer discusses the fundamentals of measurement design and data analysis methods specific to PS/QI. Consideration is given to the selection of appropriate measures when designing a PS/QI project, as well as the method and frequency for collecting these measures. In addition, this primer reviews key aspects of tracking and analyzing data, providing an overview of statistical process control methods while highlighting the construction and utility of run and control charts. Lastly, this article discusses strategies to successfully develop and execute PS/QI initiatives in a way that facilitates the ability to appropriately measure their effectiveness and sustainability.

PMID:37473436 | DOI:10.1002/ohn.430

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Nevin Manimala Statistics

Patient and Community Factors Affecting Treatment Access for Opioid Use Disorder

Obstet Gynecol. 2023 Aug 1;142(2):339-349. doi: 10.1097/AOG.0000000000005227. Epub 2023 Jul 5.

ABSTRACT

OBJECTIVE: To examine whether access to treatment for women with opioid use disorder (OUD) varied by race and ethnicity, community characteristics, and pregnancy status.

METHODS: We conducted a secondary data analysis of a simulated patient caller study of buprenorphine-waivered prescribers and opioid-treatment programs in 10 U.S. states. We conducted multivariable analyses, accounting for potential confounders, to evaluate factors associated with likelihood of successfully securing an appointment. Descriptive statistics and significance testing examined 1) caller characteristics and call outcome by assigned race and ethnicity and clinic type (combined, opioid-treatment programs, and buprenorphine-waivered prescribers) and 2) clinic and community characteristics and call outcome by community race and ethnicity distribution (majority White vs majority Black, Hispanic, Asian, American Indian, Alaska Native, Native Hawaiian, or Pacific Islander) and clinic type. A multiple logistic regression model was fitted to assess the likelihood of obtaining an appointment by callers’ race and ethnicity and pregnancy status with the exposure of interest being majority Black, Hispanic, Asian, American Indian, Alaska Native, Native Hawaiian, or Pacific Islander community distribution.

RESULTS: In total, 3,547 calls reached clinics to schedule appointments. Buprenorphine-waivered prescribers were more likely to be in communities that were more than 50% White (88.9% vs 77.3%, P<.001), and opioid-treatment programs were more likely to be in communities that were less than 50% White (11.1% vs 22.7%, P<.001). Callers were more likely to be granted appointments in majority Black, Hispanic, Asian, American Indian, Alaska Native, Native Hawaiian, or Pacific Islander communities (adjusted odds ratio [aOR] 1.06, 95% CI 1.02-1.10 per 10% Black, Hispanic, Asian, American Indian, Alaska Native, Native Hawaiian, or Pacific Islander community population) and at opioid-treatment programs (aOR 4.94, 95% CI 3.52-6.92) and if they were not pregnant (aOR 1.79, 95% CI 1.53-2.09).

CONCLUSION: Clinic distribution and likelihood of acceptance for treatment varied by community race and ethnicity distribution. Access to treatment for OUD remains challenging for pregnant people and in many historically marginalized U.S. communities.

PMID:37473410 | DOI:10.1097/AOG.0000000000005227

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Nevin Manimala Statistics

Changes in Rates of Hypertensive Disorders of Pregnancy Among Nulliparous Patients After the ARRIVE (A Randomized Trial of Induction Versus Expectant Management) Trial

Obstet Gynecol. 2023 Aug 1;142(2):239-241. doi: 10.1097/AOG.0000000000005239. Epub 2023 Jul 5.

ABSTRACT

The ARRIVE (A Randomized Trial of Induction Versus Expectant Management) trial demonstrated lower rates of hypertensive disorders of pregnancy (HDP) among low-risk nulliparous patients undergoing labor induction at 39 weeks of gestation. We conducted a population-based cohort study in which we evaluated the association between the routinization of 39-week induction and the rate of HDP by comparing rates before and after the ARRIVE trial publication, using the National Vital Statistics System. Logistic regression models were used to project what the HDP rate would have been based on trends seen pre-ARRIVE. Despite an overall increase in the rate of HDP from pre-ARRIVE to post-ARRIVE (4.9% pre vs 6.3% post, adjusted odds ratio [aOR] 1.26, 95% CI 1.24-1.27), the HDP rate was significantly lower in the post-ARRIVE group among patients undergoing induction at 39 weeks of gestation (14.7% pre vs 14.1% post, aOR 0.91, 95% CI 0.90-0.93), decreasing by 12.0% per year (P<.001). The rate of HDP among all other delivering patients was higher in the post-ARRIVE group (4.1% pre vs 5.5% post, aOR1.32, 95% CI 1.30-1.34). Our findings may suggest that, as the overall HDP rate rises, the relative advantage of 39-week induction will rise similarly.

PMID:37473407 | DOI:10.1097/AOG.0000000000005239

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Nevin Manimala Statistics

Mortuary Statistics of Natchez, Miss., for the Year Ending Dec. 31st, 1865

Chic Med Exam. 1866 Mar;7(3):144-147.

NO ABSTRACT

PMID:37473327 | PMC:PMC9994901

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Nevin Manimala Statistics

Medical Statistics in the Army

Chic Med Exam. 1867 Jun;8(6):342-343.

NO ABSTRACT

PMID:37473311 | PMC:PMC9999863

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Nevin Manimala Statistics

Letter from Edmund Andrews, M.D., on Venereal Diseases and Prostitution under the License System of Europe: The Laws, Statistics and Results of the System

Chic Med Exam. 1867 Oct;8(10):603-616.

NO ABSTRACT

PMID:37473240 | PMC:PMC9999752

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Nevin Manimala Statistics

Statistics of the Profession in Paris

Chic Med Exam. 1866 Jun;7(6):366.

NO ABSTRACT

PMID:37473025 | PMC:PMC9994912

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Nevin Manimala Statistics

Vital Statistics

Chic Med Exam. 1870 Aug;11(8):520-521.

NO ABSTRACT

PMID:37472084 | PMC:PMC10023041

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Nevin Manimala Statistics

The Relative Dangers of Anæsthesia by Chloroform and Ether-Statistics of 209,893 Cases

Chic Med Exam. 1870 May;11(5):257-266.

NO ABSTRACT

PMID:37471998 | PMC:PMC10022927

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Nevin Manimala Statistics

Prognostic impact of coronary lesions and its revascularization in a 5-year follow-up after the TAVI procedure

Catheter Cardiovasc Interv. 2023 Jul 20. doi: 10.1002/ccd.30767. Online ahead of print.

ABSTRACT

BACKGROUND: Coronary artery disease (CAD) is a common finding in patients undergoing transcatheter aortic valve implantation (TAVI). However, its prognostic significance and its management remains controversial.

AIMS: This study sought to determine whether the presence of CAD, its complexity, and angiography-guided percutaneous coronary intervention (PCI) are associated with outcomes after TAVI.

METHODS: All patients undergoing TAVI at a tertiary referral center between 2008 and 2018 were included in a prospective observational study. Baseline SYNTAX (Synergy between PCI with Taxus and Cardiac Surgery) score (SS) and a residual SS after PCI were calculated. The endpoints on the 5 year follow-up were all-cause mortality and a composite of mayor cardiovascular adverse events (MACE).

RESULTS: In 379 patients, the presence of CAD and its complexity were not significantly associated with worse 5-year survival after TAVI, with a mortality for SS0 of 45%; for SS 1-22 of 36.5% (HR 0.77; 95% CI 0.53-1.11, p = 0.15) and for SS > 22 of 42.1% (HR 1.24; 95% CI 0.59-2.63, p = 0.57). Regarding the combined event of MACE, there were also no statistically significant differences between patients with CAD and without CAD (56.8% in patients without CAD and 54.9% in patients with CAD; HR 1.06; 95% CI 0.79-1.43, p = 0.7). Angiography-guided PCI or completeness of revascularization was not associated with different outcomes.

CONCLUSIONS: In the present analysis, neither the presence nor the extent of CAD, nor the degree of revascularization, was associated with a prognostic impact in patients undergoing TAVI at 5-year follow-up.

PMID:37471716 | DOI:10.1002/ccd.30767